Malaria parasites proliferate in an unusual way. Rather than dividing into two daughter cells like human cells, they first amplify their genetic material tenfold, hundredfold or even thousandfold ...
The flavivirus Duck Tembusu virus (DTMUV) exhibits high pathogenicity and transmissibility, posing a severe threat to the poultry industry in China and Southeast Asia. Although the molecular ...
A key statistical test in research fields including biology, economics and psychology, analysis of variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between ...
4 Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany Background Hepatitis E virus (HEV) infections remain a global health concern. Immunocompromised patients are at ...
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UFMylation, the latest addition to the ubiquitin-like posttranslational modifications, plays an important role in a variety of cellular activities. However, its potential role in DNA replication and ...
In this fundamental study, the authors describe ELF3 as a candidate driver of luminal progenitor transformation, such that its up-regulation during replicative stress conditions and in BRCA1 deficient ...
During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...
ASPM is a protein encoded by primary microcephaly 5 (MCPH5) and is responsible for ensuring spindle position during mitosis and the symmetrical division of neural stem cells. We recently reported that ...
BLM is sumoylated in response to replication stress. We have studied the role of BLM sumoylation in physiologically normal and replication-stressed conditions by expressing in BLM-deficient cells a ...
Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, ...
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