Masroor Ahmad Paddar and colleagues reveal noncanonical roles of ATG5 and membrane ATG8ylation in regulating retromer assembly and function. They identify ATG5's unique non-autophagic role and show ...
This is an important study to reveal local circuit mechanisms in the POA that control body temperature and also highlight how neurotransmitter GABA and neuropeptide NTS from the same neurons ...
Departamento de Química, Fundação Universidade Regional de Blumenau, FURB, Campus 1, Rua Antônio da Veiga, 140, Victor Konder, 89012-900 Blumenau-SC, Brazil Article Views are the COUNTER-compliant sum ...
Mutations accumulate throughout life in every cell of the body. A long-standing question is to what extent these mutations contribute to aging. Age is the single greatest risk factor for cancer, a ...
Copyright © 2017 The American Chemical Society and Division of Chemical Education, Inc. Article subjects are automatically applied from the ACS Subject Taxonomy and ...
Hypoxia inducible factor-1 (HIF-1) is a key regulator in hypoxia and can determine the fate of brain cells during ischemia. However, the mechanism of HIF-1 regulation is still not fully understood in ...
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