Immunogenicity poses a significant challenge in biotherapeutics development due to the formation of anti-drug antibodies (ADA), which can alter drug pharmacokinetics (PK) and reduce efficacy. However, ...
dDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK ...
MBLEM, Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, U.K. Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) ...
Department of Applied Physics and Applied Mathematics, Columbia University, New York, New York 10027, United States Condensed Matter Physics and Materials Science Department, Brookhaven National ...
Inference of action potentials ('spikes') from neuronal calcium signals is complicated by the scarcity of simultaneous measurements of action potentials and calcium signals ('ground truth'). In this ...
Generalized structured component analysis (GSCA) is a theoretically well-founded approach to component-based structural equation modeling (SEM). This approach utilizes the bootstrap method to estimate ...
The aims of this paper are twofold. Firstly, we present an approximating formula for pricing basket and multi-asset spread options, which genuinely extends Caldana and Fusai’s (2013) two-asset spread ...
This paper describes a general model that subsumes many parametric models for continuous data. The model comprises hidden layers of state-space or dynamic causal models, arranged so that the output of ...
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