Blood-brain barrier (BBB) disruption is a critical pathological feature of ischemic stroke, yet effective therapies targeting BBB repair remain limited. Gardenoside, an iridoid glycoside from Gardenia ...
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Chromosomal rearrangements that generate novel fusion genes are a hallmark of acute myeloid leukemia (AML). Depletion experiments in cell line models have suggested that continued expression is ...
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We report the de novo microbial biosynthesis of (S)-tetrahydropapaverine (THP) and the semisynthesis of papaverine using microbially biosynthesized THP. We used protein engineering to develop variants ...
1 D3PMs - Discrete Denoising Diffusion Probabilistic Models NeurIPS'21 Proposing how to build a denoising diffusion model in discrete state space 2 τLDR - Tau-Leaping Denoising Reversal NeurIPS'22 ...