Verma and colleagues interrogate the mechanisms of phagosome maturation arrest during Mycobacterium tuberculosis infection. While cellular events that culminate in this arrest have been largely ...

Objectives The oral microbiome plays a critical role in modulating systemic inflammation, partly through its interactions ...

J. Craig Venter, the scientist who raced to decode the human genome, has died at age 79. Venter rose to fame in the field for publishing the first bacterial genome ever decoded, along with a list of ...

We performed spatial transcriptomics of estrogen receptor (ER)–negative, ER-low, and ER-high tumor regions of breast cancers that were intermediate (10%-60%) ER ...

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee. Areas of their ...

Abstract: OBJECTIVE:To explore the molecular mechanisms of Rhizoma Coptidis in the treatment of polycystic ovary syndrome (PCOS) combined with type 2 diabetes mellitus (T2DM) using network ...

Scientists have made an enormous step toward understanding the human brain by building a neuron-by-neuron and synapse-by-synapse roadmap -- scientifically speaking, a 'connectome' -- through the brain ...

The miRNA binds to AGO's seed region, prompting the exploration of small molecules that can offset miRNA repression of target mRNA. This miRNA-181c-5p was found to be upregulated in the chronic ...

Cancer Res (2024) 84 (6_Supplement): 1139. Background: The current binary distinction between HER2-positive and HER2-negative breast cancer (BC) has recently been challenged by the emergence of the ...

UC Santa Cruz scientists, along with a consortium of researchers, have released a draft of the first human pangenome—a new, usable reference for genomics that combines the genetic information of 47 ...

More than a year after it was secretly recorded and a month after it was leaked, a backroom conversation among three Los Angeles City Council members and a prominent union president continues to shake ...