The polysaccharide capsule of Streptococcus pneumoniae plays a major role in virulence, adherence to epithelial cells, and overall survival of the bacterium in the human host. Galactose, mannose, and ...

Since Jacob and Monod’s discovery of the lac operon ∼1960, the explanations offered for most metabolic adaptations have been genetic. The focus has been on the adaptive changes in gene expression that ...

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Transcription initiation involves the interaction of DNA-dependent RNA polymerase with promoters. In bacteria, this is a highly regulated process. Many regulators interact directly with the bacterial ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Arsenic is a trace element found in the earth’s crust at an ...

This review provides an overview of the structure, function, and catalytic mechanism of lacZ β-galactosidase. The protein played a central role in Jacob and Monod's development of the operon model for ...

BglG, which regulates expression of the beta-glucoside utilization (bgl) operon in Escherichia coli, represents a family of RNA-binding transcriptional antiterminators that positively regulate ...

The fold increase in recombination observed by deleting mutS is shown in parentheses and indicates the relative efficiency of mismatch correction by the MMR system. C·C mismatches are not corrected by ...

Here, we describe the regulation of genes at the posttranscriptional initiation level by the sRNA RyhB. We observed that RyhB down-regulates the mRNA levels for the genes that are known to be ...