PNAS

TGFb signaling instructs a conserved fibrosis-associated cell state marked by LRRC15

Contributed by Shannon J. Turley; received December 17, 2025; accepted April 21, 2026; reviewed by Boris Hinz and Zemin Zhang This study defines the transcriptional heterogeneity of lung ...
Frontiers

Decoding sTREM2: its impact on Alzheimer’s disease – a comprehensive review of mechanisms and implications

Soluble Triggering Receptor Expressed on Myeloid Cells 2 (sTREM2) plays a crucial role in the pathogenesis of Alzheimer’s disease (AD). This review comprehensively examines sTREM2’s involvement in AD, ...
C&EN

Extracellular Vesicle ITGAM and ITGB2 Mediate Severe Acute Pancreatitis-Related Acute Lung Injury

Department of Integrated Traditional Chinese and Western Medicine, West China Hospital of Sichuan University, Chengdu 610041, China Department of Integrated Traditional Chinese and Western Medicine, ...
Europe PMC

Intestinal single-cell atlas reveals novel lymphocytes in pigs with similarities to human cells.

Lymphocytes can heavily influence intestinal health, but resolving intestinal lymphocyte function is challenging as the intestine contains a vastly heterogeneous mixture of cells. Pigs are an ...
PNAS

Endocannabinoid system acts as a regulator of immune homeostasis in the gut

Exogenous cannabinoids such as marijuana exert their influence through cannabinoid receptors. Endogenous cannabinoids such as anandamide (AEA) function through the same receptors, and their ...