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Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Affinity chromatography is a well-known method dependent on molecular recognition and ...
The very large G-protein-coupled receptor 1 (VLGR1/ADGRV1) is the largest member of the adhesion G-protein-coupled receptor (ADGR) family. Mutations in VLGR1/ADGRV1 cause human Usher syndrome (USH), a ...
Humoral immunity relies on the mutation and selection of B cells to better recognize pathogens. This affinity maturation process produces cells with diverse recognition capabilities. Examining optimal ...
Deep learning methods, which can predict the binding affinity of a drug–target protein interaction, reduce the time and cost of drug discovery. In this study, we propose a novel deep convolutional ...
Thermodynamics is an established tool for both low-temperature and hydrothermal geochemistry (Anderson, 1998), and is more recently being recognized for applications in organic geochemistry and ...
A protocol is developed to allow the accurate characterization of partition to lipid bilayers for solutes with low affinity, using isothermal titration calorimetry. The methodology proposed is ...
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