The dangers of antibiotic overuse have become increasingly clear in recent decades. Excessive use accelerates the evolution of bacterial resistance to antibiotics, raising the alarming prospect of ...
Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy ...
The NIH 4D Nucleome consortium, of which this study is a part, aims to extend this kind of mapping into the fourth dimension: ...
Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells ...
A team of researchers led by engineers at Duke University have been awarded a Phase 1 Genesis grant from the Department of Energy to develop an AI platform to accelerate the design of hierarchically ...
Background Concomitant metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in patients with chronic hepatitis B (CHB), yet its impact on liver-related outcomes remains ...
These authors have equally contributed to this work. Bipolar disorder (BD) is a major mood disorder influenced by both genetic and environmental factors. While DNA methylation from peripheral tissues ...
DNA N4-methylcytosine (4mC) is significantly involved in biological processes, such as DNA expression, repair, and replication. Therefore, accurate prediction methods are urgently needed. Deep ...
Epigenetic modifications play a vital role in the preservation of genome integrity and in the regulation of gene expression. DNA methylation, one of the key mechanisms of epigenetic control, impacts ...
The year was 1900. Three European botanists — one Dutch, one German and one Austrian — all reported results from breeding experiments in plants. Each claimed that they had independently discovered ...
Department of Life Science, Graduate School of Arts and Science, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan Komaba Institute for Science, The University of Tokyo, 3-8-1 ...