DNA repair enzymes favor specific sequences, shaping mutation patterns in the human genome

When a wound does not heal properly, it leaves a scar. Similarly, mutations—which are permanent changes to genetic code—are ...

Scientists Trained An AI Model In DNA—And It Invented 16 New Viruses

Scientists are worried about how smart DNA-trained artificial intelligence models could get—and that they could become a ...

This Silicon Chip Grows DNA in Plain Water. It Could Rewrite How the World Stores Data.

This breakthrough transforms the building of synthetic DNA from a chemical process to an electrical one. Here’s what you’ll ...
Nature

Could mending damaged DNA prolong life?

Inspired by long-lived animals — and human centenarians — researchers are hunting for ways to enhance DNA repair and extend ...
News Medical

DNA Replication and Repair

DNA replication and repair are critical processes that ensure the correct genetic material of a biological system is carried on. DNA continually undergoes a process of replication and division and ...
PNAS

Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching

Positive-strand RNA viruses—including coronaviruses, alphaviruses, flaviviruses, and many other medically and economically important pathogens—replicate their RNA genomes by virus-encoded machinery ...
eLife

CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from

Department of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Spain; DNA:Protein Interactions Unit, School of Biochemistry, Biomedical ...
PNAS

Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication

Positive-strand RNA [(+)RNA] viruses constitute the largest genetic class of viruses and include many high-impact pathogens, such as SARS–CoV-2 (COVID-19 pandemic coronavirus), MERS CoV, Zika, ...