Frontiers

ROCKETS – a novel one-for-all toolbox for light sheet microscopy in drug discovery

Advancing novel immunotherapy strategies requires refined tools in preclinical research to thoroughly assess drug targets, biodistribution, safety, and efficacy. Light sheet fluorescence microscopy ...
PNAS

Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade

Immunotherapy, especially blockade of the PD-1/PD-L1 and CTLA-4 axes, has resulted in durable responses in a range of cancers. However, responses remain heterogeneous among patients. Treatment outcome ...
C&EN

Tutorial on Powder X-ray Diffraction for Characterizing Nanoscale Materials

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Powder X-ray diffraction (XRD) is a common characterization ...
Nature

Measuring single-cell gene expression dynamics in bacteria using fluorescence time-lapse microscopy

Numerous gene expression assays have been developed in biology; however, quantitative fluorescence time-lapse microscopy (QFTM) is the only current method for monitoring gene expression in single ...