The treatment landscape for C3G has historically depended on the off-label use of multiple prescription therapies, ...

Background Accumulating evidence has demonstrated that distinct tumour-promoting and tumour-restraining cancer-associated fibroblast (CAF) subtypes coexist in pancreatic ductal adenocarcinoma.

Vascular inflammation triggers endothelial dysfunction, a pivotal factor in the pathogenesis of diabetic vascular complications. Complement component 1q (C1q), a crucial component of the immune system ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

The components of blood include plasma, platelets, and red and white blood cells that circulate through the body. Blood supplies essential substances, such as sugars and oxygen, to cells and organs, ...

Complement may drive the pathology of hypertension through effects on innate and adaptive immune responses. Recently an injurious role for the anaphylatoxin receptors C3aR (complement component 3a ...

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease characterized by damage to the alveolar epithelium, leading to fibrosis and excessive accumulation of ...

Abstract: Seismic ambient noise has a strongly nonstationary time-frequency statistics that demand better interstation correlation methods to improve the balance of highly variable ambient-noise ...

The figure focuses on complement activation by means of the alternative pathway because it is the one responsible for hemolysis in PNH. The lightning bolt symbolizes the spontaneous hydrolytic ...

Influence of racial and ethnic identity on overall survival in patients with chronic lymphocytic lymphoma. This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting I. This abstract does not ...