Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The melt analysis feature in most real-time polymerase chain reaction (PCR) ...

Gene expression is in part controlled by cis-regulatory elements (CREs) such as enhancers and repressive elements. Anecdotal evidence has indicated that a CRE and a promoter need to be biochemically ...

In mammalian cells, mitochondrial dysfunction triggers the integrated stress response, in which the phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) results in the induction of ...

Higher education has entered into an era of transition. Changing student demographics, rapidly evolving stakeholder demands, and new technologies are requiring universities to reconsider abiding ...

Previous methods to systematically characterize sequence-intrinsic activity of promoters have been limited by relatively low throughput and the length of the sequences that could be tested. Here we ...