RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

In the study of bacteria, a longstanding dogma has held that two molecular machines—RNA polymerase, which leads the way in transcribing DNA into RNA, and ribosomes, which bring up the rear translating ...