Developing treatments for rare diseases poses many unique challenges that cannot be addressed by traditional study designs. Small populations will result in prolonged enrolment periods and/or ...

Noninferiority clinical trials have become a major tool for the evaluation of drugs, devices, biologics, and other medical treatments. Treatment with placebo or with a no-treatment control in a study ...

Doctors have long recommended that infants avoid peanuts. But in 2017, experts officially reversed that guidance, and food ...

This paper presents preliminary results of an empirical study of probability sampling designs based on the study of seven attributes of collared rimsherds from six totally or almost totally excavated ...