Operating massive reverse proxy fleets reveals hard lessons: optimizations that work on smaller systems fail at scale; mundane oversights like missing commas cause major outages; and abstractions ...
Cytotoxic T-lymphocyte antigen 4 (CTLA4) is a co-receptor expressed by activated, memory T cells and regulatory T cells 1,2,3,4,5,6. It is a homodimer that can bind to the homodimeric ligands CD80 ...