Bile acid metabolism suppression was linked to colorectal cancer prognosis and a 15 gene signature predicted overall survival ...
MicroRNA（miRNA）是众多生理与病理过程的关键调控因子，在疾病诊断与治疗评估中具有重大前景。尽管已有多种定量miRNA检测方法被报道，但由于检测时间长、灵敏度不足或复杂样品基质干扰，尚无方法适用于实时监测活细胞miRNA释放。在此，研究人员报道了一种 MicroRNA（miRNA）是众多生理与病理过程的关键调控因子，在疾病诊断与治疗评估中具有重大前景。尽管已有多种定量miRNA检测方法被 ...
Researchers found that cigarette smoke extract weakened epithelial barriers and increased the proportion of human airway ...
This guide brings together practical recommendations and workflow considerations to reduce unnecessary troubleshooting and ...
PCR optimization helps generate reliable NGS libraries by improving amplification efficiency and reducing variability.
BACKGROUND: Metabolic adaptation and maladaptation are hallmarks of the failing heart and may be a target for therapeutic ...
This valuable study provides solid evidence that N6 methylation of A74 by METTL3 is required for efficient translation directed by the SARS-CoV-2 5′UTR in unin ...
† Center for Drug Design, Academic Health Center, University of Minnesota, 516 Delaware Street SE, PWB 7-224, MMC 204 Minneapolis, Minnesota 55455, United States ‡ Department of Microbiology & ...
We also conducted quantitative RT-PCR to validate 11 of the 13 down-regulated genes in the three mutants and found overall similar patterns, as revealed by the RNA-seq data (Fig. S5 B), indicating ...
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