The Argonautes represent a highly conserved gene family that is found in almost all eukaryotes and is even found in bacteria and archaea. Many members of the Argonaute gene family are found in the ...
In neurons as well as other eukaryotic cells, intracellular proteins are primarily degraded by the ubiquitin–proteasome system (UPS), and membrane proteins by the lysosome system. Ubiquitylation tags ...
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