Mice with a version of sickle-cell disease have blood-forming stem cells that show signs of chronic stress, DNA damage and premature ageing, scientists have found 1. But existing cancer drugs and anti ...

Many middle school students spend their summer breaks catching up on their favorite television shows, lounging with friends ...

New research revealed that TRF2 does more than protect chromosomes, helping muscle stem cells repair tissue and slowing ...

Malaria parasites proliferate in an unusual way. Rather than dividing into two daughter cells like human cells, they first amplify their genetic material tenfold, hundredfold or even thousandfold ...

Blood cancers develop when changes in DNA cause blood-forming cells to grow abnormally. Instead of producing healthy blood ...

Long tenure isn't depreciation. It's compounding — when the conditions allow it. Most systems pay for accumulation instead, ...

Internal organisational developments, the major transitions currently underway and the digital challenge are forcing public administrations to change as well. The value of continuity and the need to ...

Instead, they lost the molecular characteristics that allowed them to function as muscle stem cells. This loss of identity had serious consequences after injury. Rather than rebuilding healthy muscle, ...

Preparing an enterprise for significant change is about clearing the path so the organization can move at full speed without ...

The study demonstrates that TRF2 goes beyond its traditional role of capping chromosome ends. In muscle stem cells, TRF2 ...

Researchers from Delhi and Nottingham find that targeting the enzyme Ark1 disrupts Plasmodium’s unique cell-division process in both humans and mosquitoes.

Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes ...