By examining genomic variation more closely, scientists can now identify new disease connections with greater speed and accuracy. For centuries, scientists have recognized that certain illnesses can ...

RNA-binding proteins (RBPs) are central regulators of post-transcriptional gene expression. They modulate key aspects of mRNA metabolism—such as splicing, ...

Analyses of RNA expression reveal molecules underpinning the cancer-associated process of skeletal-muscle wasting, a ...

RNA biology is a dynamic field crucial to deciphering gene expression and cellular function while revealing the intricacies of disease mechanisms. Recently, ...

A team at Massachusetts General Hospital uncovered that an immune defense protein, Resistin-like molecule gamma, attacks ...

Immune cells called double negative T cells are abundant in the intestine but have been poorly understood till date. In a recent study, researchers from the Institute of Science Tokyo report that ...

This study offers a valuable methodological advance by introducing a gene panel selection approach that captures combinatorial specificity to define cell identity. The findings address key limitations ...

It's no secret that we need new ways to treat and detect disease, including cancer. Specifically, we need better biomarkers that can be used for diagnosis and better ways to selectively get medicine ...

LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.

This valuable study addresses the effects of selection on aggression on fitness and life-history trade-offs in Drosophila melanogaster. However, the evidence presented is incomplete and does not ...

The team built a model where separate large language models for proteins and RNA “talk” to each other. From those exchanges, ProRNA3D-single generates 3D structures showing viral RNA docking onto ...