Upadacitinib and secukinumab for PsA offers comparable improvements in skin and joint symptoms, but adalimumab offers superior pain relief.

Objective To characterise the use of the prostate specific antigen (PSA) test in primary care in England. Design Population based open cohort study. Setting England. Participants 10 235 805 male ...

Objective Peer mentoring has been shown to be an effective intervention for chronic conditions with evidence to suggest that ...

Introduction A substantial number of patients with major depressive disorder experience non-remission despite treatment with psychotherapy and several antidepressant drugs. This has increased the ...

Background The minimally important difference (MID) for frailty variation associated with adverse outcomes remains unknown in ...

This valuable study examined the roles of the posterior parietal cortex in rats performing an auditory change-detection decision task. It provided solid evidence for two subpopulations with opposing ...

Objective To determine whether adding web-based support (e-coachER) to an exercise referral scheme (ERS) increases objectively assessed physical activity (PA). Design Multicentre trial with ...

Month Weight Loss in People With Obesity: The Digital Therapy to Promote Weight Loss in Patients With Obesity by Increasing Their Adherence ...

Culture Secretary Lisa Nandy has indicated that the government is considering a “mixed funding model” for the BBC, combining the existing licence fee with commercial and subscription revenues.

This study presents a fundamental discovery of how cerebellar climbing fibers modulate plastic changes in the somatosensory cortex by identifying both the responsible cortical circuit and the ...