Just as life pulsates in big vibrant cities, it also prospers in crowded environments inside cells. The interior of cells is densely packed with biomolecules like proteins and nucleic acids. How is ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Researchers have created an array of nanopillars that can breach the nucleus of a cell -- the compartment that houses our DNA -- without damaging the cell's outer membrane. This new 'gateway into the ...

The cell nucleus goes a long way during an immune response, both literally and figuratively. The white blood cells in question are cytotoxic T lymphocytes (CTLs), also known as killer T cells. These ...

Kanazawa University, report in ACS Applied Nano Materials a new method to precisely measure nuclear elasticity—the stiffness ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's ...

A newly discovered nuclear role for HSL reveals how imbalances in its location within fat cells may contribute to both ...

For 60 years, HSL was known for releasing energy from fat, but people born without it lose fat instead of gaining weight—a mystery that Prof. Langin and colleagues have now solved. After six decades ...

A team led by the UAB Institut de Neurociències (INc-UAB) has for the first time identified the mechanism behind a ...