Frontiers

Homogeneous shear distribution improves NK-92 cell cytotoxicity in a clinically relevant 2 L membrane-stirred bioreactor

The immortalized NK-92 cell line is widely used to study natural killer (NK) cell biology and develop immunotherapies. NK-92 cells exhibit strong cytotoxic activity against tumor and virus-infected ...
PNAS

Cell-based glycoengineering for production of homogeneous and specific glycoform-enriched antibodies with improved effector functions

The efficacy of therapeutic antibodies is determined by two activities, one is to capture the target through specific antigen recognition and the other is to recruit immune cells to the target site ...
C&EN

Recycling of Homogeneous Catalysts─Basic Principles, Industrial Practice, and Guidelines for Experiments and Evaluation

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Homogeneous catalysts─organometallic complexes but also organocatalysts or ...
C&EN

Safe, One-Pot, Homogeneous Direct Synthesis of H 2 O 2

Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University, 744 Moto-oka, Nishi-ku, Fukuoka 819-0395, Japan International Institute for Carbon-Neutral Energy Research ...
Frontiers

BDNF mediates improvements in executive function following a 1-year exercise intervention

Executive function declines with age, but engaging in aerobic exercise may attenuate decline. One mechanism by which aerobic exercise may preserve executive function is through the up-regulation of ...
PNAS

PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair

MutLα (MLH1–PMS2) is a latent endonuclease that is activated in a mismatch-, MutSα-, proliferating cell nuclear antigen (PCNA)-, replication factor C (RFC)-, and ATP-dependent manner, with nuclease ...