CCNs are a family of extracellular matrix proteins that regulate diverse aspects of cellular functions, and are involved in inflammation and tissue repair. Deregulation of CCN proteins is associated ...

Scientists at the University of Helsinki have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Extracellular ...

Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix. These proteins are composed of glycosaminoglycan chains that are covalently attached to a ...

Collagens and elastin in the extracellular matrix, which forms a scaffold to support organs, cause the immune system's natural killer cells to switch off their 'killer' function. The hypertension drug ...

Scientists say the origins of the ‘Hippo pathway’ date back to single-celled organisms In A Nutshell The Hippo signaling ...

New images are providing the first visual evidence of a long-postulated physical link by which genes can receive mechanical cues from its microenvironment. Created by integrating six different imaging ...

FKBP65 (65-kDa FK506-binding protein) is an endoplasmic reticulum (ER)-localized peptidyl-prolyl cis-trans isomerase predicted to play a role in the folding and trafficking of secretory proteins. In ...

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions, with a focus on collagen-rich environments and fibrosis. We have developed a new ...

From silver nanofibers to smart, sensory-packed dressings, the next generation of wound-healing technology is blurring the ...

In a recent study published in NPJ Microgravity, scientists explore the impact of spaceflight on human vascular smooth muscle cells at the transcriptomic level. Study: Spaceflight effects on human ...