Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

The coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is a highly virulent virus. Evidence suggests that disruption of host ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Salt stress remains a critical challenge for plant growth, especially in crops like pea (Pisum sativum L.). This study explores the role of histone modifications in regulating pea's response to salt ...

Epigenetics, the study of changes in gene expression that are not caused by alterations in the DNA sequence, has emerged as a key player in the development and severity of type 2 diabetes. Epigenetics ...

An international team of researchers has analyzed the function of the histone demethylase KDM5A in multiple myeloma, one of the three major hematological cancers, and clarified the mechanism by which ...

Epigenetics is a rapidly growing field of study that focuses on the heritable changes in gene expression that occur without alterations to the underlying DNA sequence. These changes are caused by ...

ASH1, Absent, small, or homeotic discs 1; CpG, 5′-Cyto- sine-phosphate-Guanine-3′ EZH, Enhancer of Zeste Homolog; GAS5, growth arrest-specific transcript 5; IFT80, Intraflagellar Transport 80; ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...

New research in C. elegans from scientists at Howard Hughes Medical Institute (HHMI) helps explain how changes in the parents’ lysosomes that promote longevity are transferred to their offspring.