Amides and thioesters are ubiquitous compounds in chemistry, used for the production of medicines, natural products, and advanced materials. Traditionally, their synthesis is a messy business, ...

Steviol glycosides, natural sweeteners extracted from Stevia rebaudiana, are widely used as sucrose substitutes due to their high sweetness and low caloric value. Among them, Rebaudioside M (Reb M) is ...

Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their energy-generating powerhouses, the mitochondria. The study illustrates how a ...

An approach that identifies, and predicts compatibility between, chemical and enzyme-sequence spaces can streamline and reduce risk in the discovery of enzymes that can catalyse a desired reaction.

A Weill Cornell Medicine team has found that triple-negative breast cancer depends on the enzyme EZH2 to spread. By silencing ...

Comparing the amino acid sequence of the cyclase with sequences from thousands of plant species in public databases revealed that the enzyme occurs precisely in plant species that form iridoids. "We ...

A major international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for ...

Chemistry researchers at the University of Utah have uncovered an enzyme, dubbed PapB, that can "tie off" therapeutic ...