Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture.
Neuroepithelial cells are stem cells that differentiate into neurons and glia, essential components of the human central nervous system, following the process of neurogenesis. Also known as ...
In a screening for a functional impact to the neuronal differentiation process, Danish researchers identified a specific circular RNA, circZNF827, which surprisingly "taps the brake" on neurogenesis.