Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year. One of the many causes for this disorder is having only one functional copy of the ...

Gene editing is a highly precise and powerful technology that allows scientists to insert, delete, modify or replace DNA ...

The NIH 4D Nucleome consortium, of which this study is a part, aims to extend this kind of mapping into the fourth dimension: ...

Researchers have mapped DNA methylation and 3D genome contacts in the same cells. The atlas uncovers cell-type-specific ...

Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year. One of the ...

Poxviruses have a long history in human disease as well as medicine: The first-ever vaccine was developed to protect against ...

Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells ...

Gene editing is like a molecular meet cute. When protein “scissors” dock onto the intended gene, even a tiny slip—no more than the width of a hydrogen atom—can ruin the connection, and the protein may ...

A new computer model recreates how Pseudomonas aeruginosa forms and spreads biofilms in realistic environments. The platform could help researchers develop better infection-control strategies and ...

Using archaeology, anthropology and DNA analysis, experts reconstructed Roman-era faces and paired them with imagined life stories inspired by historical evidence.

Every cell in the human body carries the same three billion letters of DNA, yet a neuron, a heart muscle cell, and a ...