viruses, OpenAI generative model
Digest more
DNA is the molecule that contains all the genetic information necessary for the development and functioning of living organisms. It is organized in a structure called "chromatin," which is found inside the nucleus of cells. The shape that chromatin takes ...
BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets to protect transplanted kidneys. BK polyomavirus, or ...
Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA foundation language models. These comparisons provide valuable ...
It’s tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate everything inside of them, including their neatly packaged DNA, then split in half. Rice University professor Peter Wolynes is interested ...
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its code and build new strands. To prevent these machines from ...
Radiopharmaceutical therapy (RPT) delivers protracted, low absorbed dose rate radiation over time, with cellular DNA repair capacity potentially limiting its efficacy. This article explores how lessons from radiobiology—particularly regarding DNA damage response (DDR)—inform the rational design of 177Lu-labeled RPT (177Lu-RPT)–based clinical trials,
A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane (green) and ribosomes (yellow/red). From Figure 1 of the ...
Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship-but mitochondria brought some baggage. Mitochondria brought their ...