The study demonstrates that TRF2 goes beyond its traditional role of capping chromosome ends. In muscle stem cells, TRF2 ...

Researchers have mapped DNA methylation and 3D genome contacts in the same cells. The atlas uncovers cell-type-specific ...

Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells ...

Memory B cells and tertiary lymphoid structures predicted BCG response and longer recurrence free survival in non muscle ...

The NIH 4D Nucleome consortium, of which this study is a part, aims to extend this kind of mapping into the fourth dimension: ...

Lysosomes, the cell's recycling hubs, are best known for their role in a group of rare inherited conditions called lysosomal storage disorders, where harmful molecules build up inside these ...

Scientists used GAGE-seq (genome architecture and gene expression by sequencing), a technique that measures both gene expression and physical contacts in the same single cell.

Every cell in the human body carries the same three billion letters of DNA, yet a neuron, a heart muscle cell, and a ...

The human-made cells show many hallmarks of life, but they can't make all their necessary internal structures or divide for that many generations ...

For centuries, humanity has wrestled with a profound question: what truly separates non-living matter from actual, breathing life? We used to think it took a mysterious, magical spark to bridge that ...

An open-source analysis framework developed by researchers at EMBL, HHU, and other institutions makes it easier to study how cells are organised ...

Researchers identified two major intrinsic cardiac neuron populations in mice: Npy-positive neurons regulate parasympathetic ...