Adipocytes are metabolically active cells; they produce signalling lipids and metabolites and secrete protein factors (adipokines) The relative levels of these lipids, proteins and metabolites change ...
Adiponectin is an adipokine produced by adipose tissue. The present studies examined the in vitro release of adiponectin by human omental adipose tissue explants as well as the mRNA content of freshly ...
As the body ages, brown adipose tissue activity decreases, fewer calories are burned, and this can contribute to obesity and ...
It was recently reported that a PPARα/γ agonist elevated pyruvate dehydrogenase kinase isozyme 4 (PDK4) mRNA levels in liver compared with vehicle or a PPARγ agonist [42]. In the present study, we ...
Obesity has escalated in every segment of the population including children, adolescences and adults. In obesity, impaired lipid and glucose metabolism are implicated in the conundrum of ...
Tetsuya Hosooka, Yusei Hosokawa, Kaku Matsugi, Masakazu Shinohara, Yoko Senga, Yoshikazu Tamori, Chikako Aoki, Sho Matsui, Tsutomu Sasaki, Tadahiro Kitamura, Masashi ...
Results from previous studies suggest that adiponectin levels are associated with risk factors for cardiovascular disease and type 2 diabetes mellitus; however, the genetic and/or environmental ...
Fish oils (FOs) have anti-inflammatory effects and lower serum triglycerides. This study examined adipose and muscle inflammatory markers after treatment of humans with FOs and measured the effects of ...
Health-care professionals typically refer to an extremely heavy person as being morbidly obese. The term reinforces the idea that the individual is at high risk of diabetes, fatty-liver disease, and ...
Iron overload increases the risk for insulin resistance and type 2 diabetes; however, the exact mechanisms that link the two are unknown. In this issue of the Journal of Clinical Investigation, Donald ...
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