All patients had a risk for FN of at least 20%. One group of patients was randomly assigned to the G-CSF pegfilgrastim during all 6 cycles of chemotherapy, which is the standard of care.

Lee Schwartzberg, MD, FACP: While colony-stimulating factors like G-CSF [granulocyte colony-stimulating factor] have revolutionized the approach to chemotherapy-induced neutropenia [CIN] and ...

The efficacy of G-CSF affects clinician choice only in secondary prophylaxis for febrile neutropenia in patients receiving chemotherapy, suggests a French survey.

Prophylactic antibiotics and G-CSF injections may also be used. Chemotherapy-induced neutropenia is typically treated with G-CSF and preventive antibiotics that help lower the risk of a bacterial ...

Neutrophils, once considered simple foot soldiers of innate immunity, are now recognized as complex players in cancer.

G-CSF alone for 7 days, then every 3 days Patients were quite sick, said Sarin, with bilirubin ranging from 22-23 mg/dL and an international normalized ratio of 1.82-1.92.

Similarly, prophylactic administration of granulocyte colony-stimulating factor (G-CSF) is underutilized despite guideline recommendations and literature on the cost-effectiveness of varying ...

G-CSF has a suspected immunosuppressive effect on peripheral blood stem cell allografts, including the shifting of cytokine production towards a type-2 helper cell response. 13, 14 In addition, G ...

Five days of prophylactic granulocyte colony-stimulating factor (G-CSF) proved as effective as 7 to 10 days for preventing chemotherapy-induced febrile neutropenia in patients with early breast ...

Most G-CSF-secreting tumors are urological malignancies, such as renal cell carcinoma, 1, 2, 3 but tumors involving the thyroid, lung, mesothelium, stomach and gallbladder have also been reported ...

Spectrum Pharmaceuticals Inc. celebrated a long-awaited win with the U.S. FDA’s approval late Sept. 9 of novel G-CSF drug eflapegrastim, cleared for use in chemotherapy-induced neutropenia nearly four ...