While AbMAP's focus on hypervariable regions enhances its efficiency, the study also notes limitations, such as the potential underrepresentation of framework residues' roles in stability.

Variation in human mitochondrial DNA (mtDNA) has been used to infer the origin and migration patterns in human populations. mtDNA analysis has been focused mainly on the first hypervariable region ...

A 385 insertion in the hypervariable region 1 of hepatitis C virus E2 envelope protein is found in some patients with mixed cryoglobulinemia type 2. Blood 2001; 98: 2657–2663.

Belinda Phipso, Stanley Lee, Ian J. Majewski, Warren S. Alexander, Gordon K. Smyth, ROBUST HYPERPARAMETER ESTIMATION PROTECTS AGAINST HYPERVARIABLE GENES AND IMPROVES POWER TO DETECT DIFFERENTIAL ...

MVRSION is a bench and informatic system which employs simultaneous weighted analysis eight of nine 16S hyper variable regions. We use Fluidigm Juno to amplify and index these regions in up to 192 ...