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Getting an expert opinion is essential after a rare cancer diagnosis like GIST, as each patient’s situation is unique, ...

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Unlike most GI cancers, GIST starts in supportive stromal tissue, not surface cells, and is classified as a sarcoma, says Dr.

But GIST is a bit different: it is one of a group of cancers that are called sarcomas. These cancers develop in the connective or supportive tissues of the body like fat, muscle, or bone.

Early stage GIST may be curable, but there is a risk of recurrence. The overall relative 5-year survival rate for GIST is 83 percent, but this varies by stage and other factors.

Advanced GIST can impact your work, relationships, or ability to do everyday things. But there are steps you can take to manage the mental and physical challenges that may come your way.

In this review, we first address the state-of-the-art diagnostic work-up of gastrointestinal stromal tumor (GIST), with a special focus on ancillary immunohistochemical and molecular genetic testing ...