Medically reviewed by Jay N. Yepuri, MD Primary biliary cholangitis (PBC), also known as primary biliary cirrhosis, is a chronic and progressive disease that damages and can eventually destroy the ...

In some severe cases, acute cholangitis is characterized by hypotension and confusion. Although Charcot’s triad is highly specific (95.9%) for acute cholangitis, it has very low sensitivity (26.4%).

Sclerosing cholangitis and primary biliary cirrhosis, which is now called primary biliary cholangitis (PBC), are chronic cholestatic liver diseases, but they differ in their causes, affected bile ...

Primary sclerosing cholangitis (PSC) is a chronic autoimmune disease with inflammation and stricture formation in the bile ducts inside the liver and/or in the extrahepatic bile duct which drains into ...

Once clinical suspicion has been established for primary biliary cholangitis (PBC), the " serologic hallmark" of the autoimmune disease are anti-mitochondrial antibodies (AMA), present in ...

Primary Sclerosing Cholangitis is a rare disease that has an impact on the bile duct. More than 25+ companies are involved in product development in different stages of development including ...

Primary Sclerosing Cholangitis (PSC) is a rare, chronic inflammatory disease of the bile ducts and is difficult to treat. Studies conducted by the Division of Gastroenterology and Hepatology at ...

Perspective > Medscape Gastroenterology > Hepatology Highlights COMMENTARY Primary Biliary Cholangitis: The Latest Data on an Evolving Disorder Rowen K. Zetterman, MD Disclosures January 04, 2019 0 ...

Linerixibat, an ileal sodium-dependent bile acid transporter inhibitor, improved more than itch for patients with primary biliary cholangitis, despite a notable placebo effect, in the GLIMMER trial.

Secondary sclerosing cholangitis occurs after a pathologic process or an injury, such as abdominal trauma with liver injury, mechanical obstruction of bile ducts by tumors or concrements ...

Christophe Corpechot, MD, from Saint-Antoine University Hospital in Paris, and colleagues randomly assigned 100 patients with primary biliary cholangitis who had had an inadequate response to ...