One of a ‘Kine’: Synthekine Engineers Cytokine Therapeutics to Treat Cancer and Inflammatory Disease
Cytokines are small proteins that enable cells to communicate with each other, particularly to modulate the immune system—an increasingly popular target in drug development for immunology, virology, ...
NANTES, France, November 7, 2025 – 6:00pm CET - OSE Immunotherapeutics SA (ISIN: FR0012127173; Mnemo: OSE), a clinical-stage biotechnology company developing immunotherapies for cancer and autoimmune ...
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Engineered biomaterial promotes formation of cancer-fighting immune cell clusters
Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary ...
Psoriasis, a chronic inflammatory skin condition characterized by dry and scaly skin lesions, affects about 7.5 million people in the United States. Psoriasis results from abnormal proliferation of ...
FHAB platform is the foundation of a modular, plug-and-play construct for potentiating a range of large molecule therapeutic classes, including cytokines, peptides, antibodies and vaccines. Sonnet’s ...
Structural equivalence is demonstrated through the comparison of a synthetic multinuclear metal complex (left) versus the designer enzyme in this report (right). A collaborative research team led by ...
When T-cells are activated, naive CD4 + cells will differentiate into various types of T helper (Th) cells. One notable factor influencing this differentiation is the cytokine milieu present during ...
CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. They interact and activate other cells in the immune system. The ...
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Human cytokine equipped with abiotic multinuclear metal center exhibits intrinsic and extrinsic functions
A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions by transplanting a synthetic trinuclear zinc center into a human cytokine.
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