This is a preview. Log in through your library . Abstract High densities of ion channels at axon initial segments (AISs) and nodes of Ranvier are required for initiation, propagation, and modulation ...
New research describes a key molecular mechanism in nerve fibers that ensures the rapid conductance of nervous system impulses. New research from the University of North Carolina at Chapel Hill School ...
Researchers have achieved patch-clamp studies of an elusive part of mammalian myelinated nerves called the Nodes of Ranvier. At the nodes, they found unexpected potassium channels that give the ...
Charcot-Marie-Tooth disease type 4C (CMT4C) is an early-onset, autosomal recessive form of demyelinating neuropathy. The clinical manifestations include progressive scoliosis, delayed age of walking, ...
STED microscopy is an important technique that can overcome the diffraction limit and resolve structures on the order of ~40mm. It is a powerful method that is particularly useful in a biological ...
The Feltri lab seeked to understand how cell-cell and cell-extracellular matrix interactions contribute to cell shape and polarity within a developing tissue. They applied these biological questions ...
CHAPEL HILL, N.C. -- New research from the University of North Carolina at Chapel Hill School of Medicine describes a key molecular mechanism in nerve fibers that ensures the rapid conductance of ...