This is a preview. Log in through your library . Abstract Applied sciences, including longitudinal and clustered studies in biomedicine, require analyses of ultrahigh-dimensional linear mixed-effects ...

Ask yourself the following questions. If you need some background, look up material on "mixed effects","hierarchical models" in wikipedia. What is a linear model? What is an additive effects model?

Limitations of linear regression applied on ecological data -- Things are not always linear : additive modeling -- Dealing with heterogeneity -- Mixed effects modeling for nested data -- Violation of ...