Diastolic dysfunction is a heart condition that happens when there is a “stiffening” of the major pumping chambers of the organ (ventricles). This stiffness gets in the way of the heart’s ability to ...

It is a common perception that approximately 50% of heart failure (HF) patients present with a normal or near-normal left ventricular (LV) ejection fraction ("HF with preserved systolic function"), ...

Diastolic dysfunction increasingly is recognized as an important cause of congestive heart failure (CHF). In this study, Mayo Clinic researchers surveyed a random sample of 2042 adults (age, 45 or ...

M ore than 6 million adults in the United States have heart failure. Of these, about half have diastolic heart failure and the other half have systolic heart failure. In February 2021, the U.S. Food ...

Nocturnal hypertension is an important predictor of the progression of left ventricular diastolic dysfunction in patients with diabetes without HF. An important predictor for the progression of left ...

Reference: “Rbm20 antisense oligonucleotides alleviate diastolic dysfunction in a mouse model of cardiometabolic heart failure (HFpEF)” by Mei Methawasin, Stefan Meinke, Michael H Radke, Gerrie P ...