Gastrulation is a process common to nearly all metazoan organisms during which an embryo with distinct tissue layers develops out of a seemingly unstructured assembly of cells referred to as 'blastula ...

Jay Shendure is in the Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA, and at the Brotman Baty Institute for Precision Medicine, the Allen Discovery Center for ...

It’s one of life’s most defining moments—that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for ...

Gastrulation, the process where an embryo reorganizes itself from a hollow sphere into a multilayered structure, is considered a 'black box' of human development. This is because human embryos are ...

(Philadelphia, PA) – Researchers at the Lewis Katz School of Medicine at Temple University have discovered that the Hippo signaling effector YAP1 is a master regulator of Nodal signaling in human ...

With the construction of a building, one of the first steps before creating the upright structure is to set the foundations and the floorplan. Mammalian development is not so different. A ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, No. 18 (Sep. 15, 1992), pp. 8736-8740 (5 pages) To study the role of keratin filaments in Xenopus development, ...