Gastrointestinal motility occurs by the coordinated contractions of the tunica muscula ris, which forms the outer wall of the alimentary canal from the distal oesophagus to the external anal sphincter ...

- Muscle cells, also known as myocytes, are specialized cells designed for contraction and force production. Skeletal Muscle Cells: These cells are long, cylindrical, and have a striated (or striped) ...

The transverse tubules (t-tubules) are invaginations of the cell membrane rich in several ion channels and other proteins devoted to the critical task of excitation-contraction coupling in cardiac ...

Real-time imaging of sub-cellular reactive oxygen species, Ca2+ signaling, and excitation-contraction coupling in skeletal muscle under physiological and pathophysiological conditions. The research in ...

BUFFALO, N.Y. -- In the 21st century, human tissue can be generated from stem cells and severed limbs are successfully reattached, while the physiological processes governing life's most fundamental ...

The ability to modify the intracellular concentrations of divalent calcium ions is vital to normal cell functioning. In the cells of the cardiac muscle, calcium ions play a crucial role in coupling ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

L-type Ca²⁺ currents determine the shape of cardiac action potentials (AP) and the magnitude of the myoplasmic Ca²⁺ signal, which regulates the contraction force. The auxiliary Ca²⁺ channel subunits ...

Actomyosin is a protein complex composed of actin and myosin. It is found in muscle fibers where it plays a role in muscle contraction. Actin is one of the most abundant proteins in eukaryotes. It ...