As the immune system ages, it reacts more slowly to pathogens, vaccines become less effective, and the risk of cancer ...

Multicellular organisms are a mosaic of different cells, tissues, and systems, each with their own specific function and interactions with other cells within the organism and/or the larger environment ...

It must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.

It is comparatively easy to tell a cell's state of health: On their surface, cells present fragments of almost all the proteins they contain inside. This means the immune system can directly recognize ...

Unlike infectious agents, cancer cells originate from the patient themselves and can therefore evade immune surveillance. The major challenge of immunotherapy is to make them detectable by the ...

Once thought to be a flaw in the system, new research suggests that CD4 T cells may actually hold the key to maintaining a ...

The aim of immunotherapy strategies is to leverage cells in the patient's own immune system to destroy tumor cells. Using a preclinical model, scientists from the Institut Pasteur and Inserm ...

An international team of researchers reports that the immune cells of older adults with a history of endurance training are more effective at combating inflammation. Regular physical activity not only ...

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and proliferate ...

When the immune system overreacts and starts attacking the body, the only option may be to shut the entire system down and risk developing infections or cancer. Immune cells that are designed to ...