Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...

Proteins, with their extraordinary diversity of structure and function, pose some of the toughest problems in the field of bioinformatics, giving rise to a growing arsenal of computational tools for ...

Bioinformatics researchers who perform alignments of long protein sequences face a difficult choice: They can get accurate results in hours (sometimes days), or quick results if they're willing to ...

Aligning multiple nucleotide sequences is a prerequisite for many if not most comparative sequence analyses in evolutionary biology. These alignments are often recognized as representing the homology ...

In bioinformatics, multiple sequence alignment (MSA) is an NP-hard problem. Nature-inspired approaches can provide an approximate solution compared to conventional approaches. In this article, the MSA ...

The coronavirus disease 2019 (COVID-19) pandemic has ravaged the globe for more than a year, with an increasing emergence of new variants of concern that stand to undermine current measures aimed at ...

The UK National Health Service is collaborating with university partners to transform public health and personalized medicine with the power of high performance computing. Bioscience teams at NHS and ...