Nature

Mechanistic diversity in ATP-binding cassette (ABC) transporters

ABC transporters use ATP hydrolysis to translocate substrates across cell membranes. Kaspar Locher reviews the mechanistic diversity of ABC transporters, as has emerged from recent structural studies, ...
Nature

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

Figure 1: YACs were selected from a public YAC contig (Whitehead Institute, GDB) to cover the candidate region and were obtained from the German human genome project. Figure 3: Insertion of a 110-bp ...
JSTOR Daily

Dynamics of α-helical subdomain rotation in the intact maltose ATP-binding cassette transporter

This is a preview. Log in through your library . Abstract ATP-binding cassette (ABC) transporters are powered by a nucleotide-binding domain dimer that opens and closes during cycles of ATP hydrolysis ...
BioTechniques

Targeting ABC to tackle AMR: taking advantage of bacterial membrane proteins

Heather Pinkett tells us about her research investigating ABC transporters in pathogenic bacteria and what this could mean ...
JSTOR Daily

An ATP-binding cassette subfamily G full transporter is essential for the retention of leaf water in both wild barley and rice

Land plants have developed a cuticle preventing uncontrolled water loss. Here we report that an ATP-binding cassette (ABC) subfamily G (ABCG) full transporter is required for leaf water conservation ...
The Scientist

Correcting the Mutation Behind a Genetic Eye Disease

Among the forms of monogenic macular degeneration, the most common is Stargardt disease. This disease is caused by mutations in the ATP-binding cassette transporter alpha 4 subunit (ABCA4) gene, ...