Nature

Mechanistic diversity in ATP-binding cassette (ABC) transporters

ABC transporters use ATP hydrolysis to translocate substrates across cell membranes. Kaspar Locher reviews the mechanistic diversity of ABC transporters, as has emerged from recent structural studies, ...
Nature

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

Figure 1: YACs were selected from a public YAC contig (Whitehead Institute, GDB) to cover the candidate region and were obtained from the German human genome project. Figure 3: Insertion of a 110-bp ...
JSTOR Daily

Dynamics of α-helical subdomain rotation in the intact maltose ATP-binding cassette transporter

This is a preview. Log in through your library . Abstract ATP-binding cassette (ABC) transporters are powered by a nucleotide-binding domain dimer that opens and closes during cycles of ATP hydrolysis ...
BioTechniques

Targeting ABC to tackle AMR: taking advantage of bacterial membrane proteins

Heather Pinkett tells us about her research investigating ABC transporters in pathogenic bacteria and what this could mean ...
JSTOR Daily

An ATP-binding cassette subfamily G full transporter is essential for the retention of leaf water in both wild barley and rice

Land plants have developed a cuticle preventing uncontrolled water loss. Here we report that an ATP-binding cassette (ABC) subfamily G (ABCG) full transporter is required for leaf water conservation ...
ascopubs.org

Downregulation of ATP binding cassette subfamily a member 10 acts as a prognostic factor associated with immune infiltration in breast cancer.

Integrated analysis of pivotal biomarker, immune cell infiltration, and therapeutic drugs for LSM1-mutated in breast cancer. This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting I. This ...